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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e7b130986da6bc7d278590d747bcf78fb8f394d186eb6cfd5b076c52c3454b' 
  AND token = 'o4Igk42UpBGweeoaWFre660Egg5CqTQil9bUpwQIhk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}