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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149d72dc43f83f9d832f7196b0647b427dc963fa4611350f6caf670d78e20fcf' 
  AND token = 'ii7grvB9gWrtjmgjMTBBC28DmGLJLfaxVdGwH4C6C84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}