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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60020234046edba483cdedf21437bcb3232a033e35e51ccbdabf0fc7c4a6653' 
  AND token = 'MEjBYxhlcVfGYWgZO3/4pniKqgCTxhU7xgq49bUCN2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}