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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f1f975e6bcbe3ac4fc600b3fcb5653244464dcd83f1dcf91569a02f64224f5' 
  AND token = 'jF2JKDe/ZrLwppEm2310UgK2rfbGD0kHVC3bWK6vcas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}