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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e31809475698aa928d5097ed0bd05e0fa399a30d1a391abb7d35315ed4ee7659' 
  AND token = 'b25h6Rdcu8jz12ZR/FeHUnhe3JsP6CeYEdXY03p9pWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}