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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a88c405611b2b296aaca08a3dc5151a519038379a1240ea4c463cc94aefc71a' 
  AND token = 'DFdIURItCWBhiR8s4hvkN/uXG/f+SiKdiGnEsStUmxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}