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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc214a1a519985bb2c27e09639d9bb730e9c400a7c33c116ee4c729c537127b0' 
  AND token = 'tQcX4dyQa5AxJpv+O5w2Tm5r5Ej2WiDq0RhCexJW95s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}