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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604222717182e456d75bc9c5ae4c998dca019192bf96de926af57be494ff9b21' 
  AND token = 'cGG1IVpBZLfpuUTrkqKp6W2Hqh02qN7xDkSJlZ9UHls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00119

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}