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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45637752b0b338ccbee7d17733756d0ba28e50cd234f52499d318988be22c7f0' 
  AND token = 'zvoUKaE9vnoqF72nndwcW/GYPpSK9W+7R8ER8rbSveM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}