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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbfb2ab7c62ebc7fe137f83c85412a7121da4ee11a0742493213289658f95d00' 
  AND token = 'O8tgiQUiy8Lsz7Uz6tIG2Cah/9Nb4gBNyjp6kP4tjSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}