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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca31883b3eeb2f79e6c188f4c0261cc8dcae859fa98e1fef408ad103325c9ed' 
  AND token = 'PqmohzjORdFvK4Ky6bairVyMk+m2clxl3pQMQm6NSAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}