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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '732392508fbe3096a51d9e1dc7c6756f3ff9b883247affce6c5860f26ae8b060' 
  AND token = 'r1+nrLo0Pxo2IPTLQN2idgKIqpUckpZoHo1k4u16RNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}