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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec733741760a5ee74f242437a522c26554bdb4b876e0a4bddec43ff4dc95fa2f' 
  AND token = '9WwVceGuQe3kwhleJFAzOj1mQ0Cs6UpQAxnO4kjfnDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}