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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616fbb7555fda292a2add6b5af257575bfeb1f5d177d59f6d3c61bfc5571cfc8' 
  AND token = 'LHssAHEaUmrn+OxHE0AEFBhZ/JQQhLdBrT/gGE396Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}