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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc2123d7df852640cf8bb98f9664e58fc34186a5fdd3e90b85ccab69cd67561' 
  AND token = 'ICdM0Qsr04zA6hb4bzgPzUNp7i+xhmaixwzXw4M35v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}