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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491f35064d3aa12314932891795431915262b3dc1986a0e0ca47874c65c476e1' 
  AND token = '/A8AYVYkkvfGLN5a2EzEcF58gi53azwlqRKesIBEBsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}