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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71ee3d1c2f3e28eaf0c67c4ead680f95678fc60b9550a8e2c559009d8bbbe9af' 
  AND token = 'actXpW2EiQJWsCXQot8oTkFtZfAuQzByZ7y639B2knU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}