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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2e2ab702dac4a68222a10ca553e89049347a9f19dee1f93220e581a3c701de' 
  AND token = 'A+WhhvGVHGuyBt17MUkw6ON1fpO79Y53+cMDqPbYxxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}