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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3863b60681656f5bf8bcd3995189fe3196f85f741ca3267d859f198c55715a52' 
  AND token = 'Nn7DM1D0UPaoDVhnAsBI6aNc9i69FDMQHWNtjm83TTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}