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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00f4b1f445daf6740fd1e7cbc842dc68fdf77fb19f7aad823a461f12b639400' 
  AND token = 'uPzLHroFRNPngKooSo1UqZ+mFJfU4w7rin41m+7cRKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}