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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da51e271463ab7ff78f0cd8635e3a80df8171a1823227b6c27675c498ddce271' 
  AND token = '/yA+GsxlKWHK5+hGGFZ0rBe+CMyW3u4m0DNlLUyHZ3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}