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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e4782768f8042bda4014cb10522bcb29eb1dee19130542b7841a280165f95c' 
  AND token = 'y10D44u+/f6wjs8Uh8ujcXCOKrKbGVpHv97mLQ3iZtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}