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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2faaf49855434fa60b9a7b8e7aa8f5f0e6c1bde477001c13c9afe0c17b0fd62d' 
  AND token = 'DBMCLxYx8MRIQ/8mulfYy7kEXc1AVg94+DXhG6KCdnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}