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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b8d3dabc02485d7b1360e87f7f4d79ff65226a97803ad12ce7fa8cb5e7d104' 
  AND token = 'b0vX4+MuIvAE3OM1cZgbL4HO/OxwRW9Dh97KBw3i2MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}