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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887651029767891e63b254cdf0b1f3316fe84a01bff4f17b9008264c752b9dcd' 
  AND token = 'kk5EMoF4Kod26LH5oNI41poAX/8171LCSokj6O4kyEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}