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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61d863629bdee77e8a697489eb78e1b5b2986d7cfa660695f7b670b7bfaf0fd' 
  AND token = 'XPHGx9P70I4DrtJmubXyZXxV/ujifF7S32XnaFpBtgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}