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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1899a379cacdad64afabae25196f4b99f1677d8595f199035c449f30e0e7cac' 
  AND token = 'HzCO4p3os58Magv+20L43cM5/0DED4TB/3PizGHI24I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}