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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101b50310ef2b4cbcde7fe6540fbda3b22f5bdb181fe2e06241ab7264db562fc' 
  AND token = 'Afkofko7L0QJBlbRSGq1AHguH+6oR7tzjkdWI8+yWbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}