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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa3879ef212250e1c722dabc16d7a56d00717918cd8e2577b37bf7add5bef972' 
  AND token = 'rPHy1Qwb1Ovyx+OADcgtuCqVhd+G8NWf43WHxjOGiek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}