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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23715accf42cbdbaf45dfc2549ac3a0d1a76a74d1ce106d53afb413c912ecd7e' 
  AND token = 'E/fez5eJQfiTKSuxp5OY1IByDFRrJoPod90NjAJRRIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}