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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '083218c370ed2ac6b23293ad24512c01bf804e2add3099ebe0b4c1e15aab5222' 
  AND token = 'TwqZQufxi/v+PnYmF8eOpvRYGjioVsNBXtNYAps5bm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}