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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d7125169fedb9b2282c5ccc67306416b48b20db562671e812462ea898f2cc5f' 
  AND token = '1wzfSD0Drr+ZBLusXn6TOue0gKs7TpvO0u3rr4JUeg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}