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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42443a0f5ad8e955c6e94eed14e733313556f7065af1f06d2e03d315b25f65ab' 
  AND token = '0lfUAVjVy326msSU3RyDQwTLK8HDkH/3MGNd19EeViU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}