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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4fd32364103338078f44d652cc7c3dd26b9298d13b96a1d809e9f53486df6af' 
  AND token = '22Adpylzu4dmlVZhO0/3MjX+UTRPCUNwSg5yZtUKN3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}