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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef69eb9549773bdbfbf8f4c3a817287cd60c0e761cd9ba7497551ec5ce2fd3f3' 
  AND token = 'Ap17qcOAN9q0QOepymTPJ5p3J6nlsqdQRYQ3tM+ESHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}