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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221b81b7b077fcb0237ff0128cd62d516b439e3f114e06ecbae0224baebeb4ee' 
  AND token = 'UejbEU0HzL0IjwlVUeXJusUbMArcsB77BVqR70lz4Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}