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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01ec27461884ab24b911ed9c9dc659b34613efdfd175aff9a1adbb79e589f94' 
  AND token = 'fdclqG2LImyRuYVVYACozuFD9F2OyldV2mJYolMu0F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}