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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1da68d033d2adc42fbb09b955b924956fccbaa6e6700bf4fbf051087fb6a85e' 
  AND token = 'u+zghB6AiS91bWFmhxScHOZ7RoQm+6UchVAPbz2AZK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}