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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101248413f750a8fec1983395c56ada0416fa016076c4fe6053f7fe0756ad45b' 
  AND token = 'SJ6jzQDv0HW2dbQRcDyFKCWI46CyFd4HiiioO+CxLrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}