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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7325a2e938180f2628e421ff5b44f2d850ca25ea9d00b9b6a74510b138a9a4dd' 
  AND token = 'lkIzksvlT3djuZWWV6kW0DAFDC4WqJUI1jQaiP9UKpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}