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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc605c7c54a800b5eddfcfe37fc8773e7b556d61ae865179925b54badd221c2' 
  AND token = '1JwaDJpLVikg/9vVvtVRF8v4s2xJ1mF44Pcl5wrr8oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}