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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ce9b4dc91ee2a162deaf10206871848d0c8f7e61ab119e72343fefb127c8c69' 
  AND token = 'u4fkfQvt/XkkUZCL0vSYB4bMVlWoz9MjQ+Woqbn6M5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}