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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749e609172a750436f72023b387e410bfb56ed2aef58fb7b47719c5cbdd1de8e' 
  AND token = 'zrbTwB3dZqCphei37fU92fQHYP122P1iUoL/hnGpPIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}