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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46f4153a5c1d2a91d1a140785ae590af8ab47f2d7e61354e3cf5ce44099eacc' 
  AND token = 'tvhnwfBcw1/BUVRf/h9tGy8cufkDOZAk3vCd4SSwzRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}