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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bed75b84193a0e5d4adb124c98e6615662c688c27885cbc5005a4cf6ab8ab170' 
  AND token = 'd/4rm61KzSYXRDfTtTqOS+UR+cmqMEhVijUw5y0ROKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}