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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db356e5ae5f70202b33ee2c8012ec8756ec68cb36f8d2a948df0a2847bba0240' 
  AND token = 'ki7h4nwKIN8QII0xykE31Y0BUUfIF+CSRLOG9/lt03Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}