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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23312a293a94b95e95c7d8e8e225dd7e36abfe27f48710038473f330dd73eab2' 
  AND token = 'oMi/WXvSWDbA2AmaMf8MyBLvMZ2BF0x0gm55flwJn18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}