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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f589601c780a9126933dcea8d323563cc944d4b8dbccd10b1bc28a556b8a5da' 
  AND token = 'JEd4izhQqfx+f+VgVVx/Bch3Kd6m6ubTqS3PdcaGzUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}