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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71291f4a74be07a75c064090b4bfa0db9be6eae2226357464655f1b654036dd0' 
  AND token = 'BNqxSV+RRHIUQ+gtSxBqYv2vIBKQ5KJOUiimlimJ4G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}