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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd37d4ab49111d8beb57488e9cd856e7eed8fae38faef34f3233e7e687ae4cb7c' 
  AND token = 'VlIyz81P/jfnkGaNzs6DjqGa8PypsLXWvMpO2KYoL4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}